Over the course of the nineteenth century, figures such as artist Frank Bellew and editor T. W. Strong introduced sequential comic strips into humor magazines and precursors to graphic novels known as “graphic albums.” These early works reached audiences in the tens of thousands. Their influences ranged from Walt Whitman’s poetry to Mark Twain’s travel writings to the bawdy stage comedies of the Bowery Theatre. Most importantly, they featured new approaches to graphic storytelling that went far beyond the speech bubbles and panel grids familiar to us today. As readers of Lost Literacies will see, these little-known early US comic strips rival even the most innovative modern comics for their diversity and ambition.